Clarithromycin is part of the class of antibiotics known as macrolide. This medication is employed to combat infections caused by specific bacteria. It does this by blocking or slowing the development of bacteria that could cause certain infections. Clarithromycin can be prescribed to patients suffering from sinus-related infections and ear problems pneumonia, bronchitis, and skin infections like impetigo or cellulitis.
Clarithromycin is also used to treat and prevent certain diseases (mycobacterium complex, also known as MAC) that are associated with the human immunodeficiency virus (HIV) virus. Clarithromycin can be utilized together with other drugs to eliminate H. Pylori, which is a bacterium that can cause gastric ulcers.
The medication is available under multiple brand names , and/or in various forms. The brand name that is used for this medication might not be available in all the forms or be approved for all conditions listed in this article. Additionally, certain forms of this medication might not be suitable for all conditions listed here.
Your physician may have recommended this medication to treat conditions other than those described in these informational articles on drugs. If you’ve not talked to your doctor about this or aren’t certain what the reason is behind currently taking the medication talk with your physician. Don’t discontinue taking this medication without consulting with your physician.
Do not give this medicine to anyone who is not your own even if they suffer from similar symptoms as you have. It could be dangerous for patients to take this medication if the physician hasn’t prescribed the medication.
What form(s) do these medications take?
250 mg
Every oval yellow film-coated tablet, by a “M” in one corner, has 250 mg clarithromycin. Nonmedicinal ingredients: cellulosic Polymers such as croscarmellose sodium D&C yellow No. 10, magnesium Stearate povidone, pregelatinized starch propylene glycol dioxide, sorbic acids, sorbitan monooleateand stearic acid and titanium dioxide and vanillin. This medication is not a source of tartrazine.
500 mg
The oval-shaped, light yellow film-coated tablet, by a “M” in one corner, is packed with 500 milligrams of clarithromycin. Nonmedicinal ingredients include cellulosic polymers and colloidal silicon dioxide the sodium croscarmellose, D&C Yellow No. 10, magnesium Stearate propylene glycol, povidone sorbitan monooleate, sorbic acid titanium dioxide, vanillin. This medicine is not a source of tartrazine.
What should I do with this medicine?
Adults The recommended dose for adults of clarithromycin tablets ranges from 250 mg-500 mg twice every day (every twelve hours) for 7 to 14 days dependent on the disease being treated.
The dosage for adults recommended for the extended-release clarithromycin is 1000 mg (2 tablets) every day for 5-14 days, dependent on the condition being treated.
To treat and prevent the development of MAC for MAC, the recommended dose of clarithromycin is 500mg twice per day. If used in conjunction with other drugs to eliminate H. Pylori The usual dosage for clarithromycin will be 500 mg per day for 10 days.
For children: the recommended daily dosage to children should be 15 mg/kg of weight (to 1000 mg daily). The daily dose for children should be divided into two equal doses that are administered every 12 hours. The duration of treatment is typically five to 10 days according to the disease being addressed. To treat and prevent the occurrence of MAC the standard dosage of clarithromycin is 7.5 milligrams per kg of body mass twice a day (up up to 500 mg once a day).
If the child is being given an orally administered suspension of clarithromycin make use of an oral syringe take a measurement of each dose of the liquid. It provides the most precise measurement than the standard teaspoons.
Clarithromycin tablets as well as clarithromycin suspension (given every two days) can be taken without or with food. If you take this medication in conjunction with food, it can cause less stomach upset.
The extended-release tablets of clarithromycin should be consumed with food. The tablets should be swallowed whole , and not broken or crushed.
Take your time with this medication even if you are beginning to start feeling better.
Numerous factors can alter the dosage of medicine one requires including body weight, medical conditions, and medication. If your physician has suggested an amount that is different than the one listed below Do not alter the method in which you are taking the medication , without consulting your doctor.
It is essential to take this medication as directed by your physician. If you are unable to take a dose, make sure you take the medication as soon as you can and follow your normal schedule. If it’s getting close for your next dose do not take any missed doses and go on by following your regular schedule. Don’t take a second dose to cover an absence. If you’re unsure what you should do after missing the dose, call your doctor or pharmacist to seek assistance.
Keep clarithromycin tablets in a cool, dry temperature. Protect them from moisture and light also keep them from reach of young children.
Keep clarithromycin oral suspension in a cool, ambient temperature. Keep the bottle tightly shut and shielded from light. Don’t refrigerate. Any oral suspension that is not used must be disposed of within 14 days. Rinse the oral syringe that measures doses every time you use it. Don’t store the suspension inside the syringe.
Don’t dispose of medicines in water (e.g. in the sink or the bathroom) and in your household waste. Ask your pharmacist about how to dispose of medicines that are no longer required or are expired.
Who should not use this medicine?
Don’t take clarithromycin when you:
are sensitive to clarithromycin, or any other ingredient in this medication
are intolerant to macrolide antibiotics in other forms, like azithromycin and erythromycin.
Have experienced the condition of jaundice (yellowing of the eyes or skin) or liver issues that are due to taking clarithromycin.
suffer from severe liver failure as well as diminished kidney function.
Have or had QT extension (an irregular electrical stimulation in the heart) or an abnormal heart rhythm.
suffer from untreated hypokalemia untreated (low potassium levels)) as well as hypermagnesemia (low magnesia levels within blood)
you are taking any of the following drugs:
astemizole
Cisapride
colchicine
domperidone
ergot alkaloids (e.g., dihydroergotamine, ergonovine, ergotamine, methylergonovine)
oral midazolam
Lomatide
pimozide
Saquinavir
“statin” cholesterol-lowering drugs (e.g. lovestatin, simvastatin)
Terfenadine
Tigragrelor
What kind of side effects could be a possibility associated with this medication?
Certain medications can cause adverse reactions. A side effect is a negative reaction to medication when used in the normal dosage. The effects may be mild or severe, and may be temporary or long-lasting.
The adverse effects listed below aren’t experienced by all who uses this medication. In case you’re concerned over any side negative effects, you should discuss the potential dangers and benefits of this medication with your physician.
The following adverse effects are reported by at minimum one percent of those taking this drug. A lot of these adverse effects are manageable however some might disappear by themselves with time.
Talk to your doctor if notice these symptoms, and they’re severe or uncomfortable. Your pharmacist could be able to give you advice about managing the these side effects.
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Abdominal discomfort
Change in the sense of
diarrhea (mild)
dizziness
gas
headache
hearing trouble
heartburn
nausea
Ears ringing
vomiting
While most of the adverse reactions listed below don’t occur frequently, they can cause serious issues should you not seek medical treatment.
Talk to your doctor promptly in the event that any of these reactions occur:
stomach cramps or severe abdominal cramps and severe stomach or abdominal cramps and
skin rash
signs of liver issues (e.g. abdominal tenderness the appearance of eyes that are yellow or itching or dark urine)
Myasthenia gravis symptoms (e.g. muscle weakness and drooping eyelids and vision problems, trouble swallowing and chewing, and trouble breathing)
Watery and severe diarrhea which could be bloody
Stop taking the medicine and seek medical attention right away in the event that any of these occur:
Heartbeats that are irregular or irregular
signs of an extreme symptoms of an allergic reaction (e.g. the hives, itching difficulties breathing, sore throat as well as swelling or redness of the mouth, face tongue, throat, or face)
symptoms of a severe reaction (e.g. peeling, peeling or blistered skin)
Certain people might have side effects that are not the ones that are listed. Consult your physician when you experience any symptom that you are concerned about when you take this medication.
Are there other precautions or cautions to take with this medication?
Before you start using any medication, you should be certain to inform your physician of any allergies or medical conditions you might have and any medication you’re taking, whether or not you are nursing or pregnant, as well as any other pertinent information regarding your health. These aspects can affect the way you take the medication.
A heart rhythm that is abnormal: Clarithromycin may cause a heart rhythm problem known as QT prolongation. If you’ve been diagnosed with an previous history of QT prolongation, have a medical condition related to QT prolongation or are taking any of the medicines (e.g. amodarone, amiodarone, sotalol) consult your physician what this medication could do to any medical issue, and how your medical condition could impact the dose and efficacy of this medication, and if you require any specific monitoring.
Allergies: If your suffered from an allergic reaction to azithromycin or erythromycin or azithromycin, you could be more likely to suffer some sort of reaction that is allergic to this drug. If you experience symptoms that indicate an allergy, such as a rash or aphthous, speak with your physician. If you notice hives, difficulty breathing, or swelling of your mouth, face, throat or tongue, you should discontinue taking the medication immediately and seek immediate medical attention.
Bacterial resistance: Inappropriate use of an antibiotic , such as clarithromycin can lead to the development of resistant bacteria that can not be destroyed with the antimicrobial. If this occurs it is possible that the antibiotic will not be effective in the near future. Although you may feel better after you begin taking clarithromycin. However however, you must continue using the medicine precisely as directed by your physician, to complete the process of ridding your body of infection and to stop the growth of resistant bacteria. Avoid taking clarithromycin and other antibiotics to treat viral infections such as common cold. Antibiotics are not able to kill viruses and their use to treat viral illnesses could result in the development in resistant bacteria.
Diarrrhea: Similar to other antibiotics like clarithromycin, it is connected to a severe infection known as Clostridium-associated diarrhea which is caused by organism C. difficile. This may occur as long as two months after the most recent dose of this drug.
If you are experiencing fluid, swollen bowel movements particularly if they’re stinky, green or bloody, and are associated with fever, whether in or after taking clarithromycin, seek medical assistance as soon as you can.
Confusion, dizziness and disorientation medication may cause dizziness, confusion or disorientation. Avoid driving or operating machinery until you’re certain that this medication doesn’t interfere with your ability to complete these tasks safely.
Kidney function kidney function kidney function could result in this medication building within the body, leading to adverse consequences. If you suffer from decreased kidney function, consult your physician how the medication can impact the medical conditions you suffer from, and how your medical condition could impact the dose and efficacy that this drug has, as well as if you require any specific monitoring.
Liver disorders: Liver disease or a reduced function of the liver could result in this medication building up within the body, leading to adverse negative effects. If you suffer from a decreased liver function, talk to your physician how the medication can influence any medical issue, and how your medical condition might influence the dosage and effectiveness the medication. Also, discuss if it is necessary to monitor your liver. This medication should not be taken by those suffering from severe liver disorders.
If you notice signs of liver issues (e.g. lack of appetite nausea vomiting, discoloration of the skin or eyes blood, the appearance of dark urine and itchy skin or abdominal discomfort) Contact your doctor immediately.
Myasthenia Gravis: This medication can cause more severe or exacerbating symptoms of myasthenia graveis. If you notice that your symptoms are getting worse or you notice new signs such as double vision eyes that are drooping, muscle weakness and difficulty eating or swallowing, consult your physician.
Women who are pregnant: Clarithromycin should not be used during pregnancy, in particular during the first three months , or until an alternative therapy that is appropriate. If you fall pregnant while using this medication, consult your physician.
When breastfeeding, this medication gets through the breast milk. If you’re breastfeeding mother and you are taking clarithromycin, it could affect the baby. Discuss with your doctor whether it is safe to continue breastfeeding.
Children Safety and efficacy of using clarithromycin suspension for oral use have been questioned for infants younger than six months old. In the case of pneumonia clarithromycin oral suspension hasn’t been examined for children less than three years old. The effectiveness and safety of using clarithromycin for preventing MAC infection is not examined for children less then 20months of age. The effectiveness and safety of taking clarithromycin tablets has not been proven for children who are younger than 12 years old.